| Market | Public Profile | Founders | Links | ||
|---|---|---|---|---|---|
The AI-native platform for next-generation protein characterization. | B2B | 10x Science develops frontier AI models with deep memory to redefine how scientists understand and engineer biology across the life sciences, starting with drug development. AI-powered drug discovery is flooding the p… | 3 | ||
Infrastructure and UI building blocks for the agentic internet | B2B | 21st.dev is the largest React component registry for AI applications, used by 2M developers (370K MAU). We provide the building blocks to create AI agents and agent-powered apps: UI components, agent templates, and an S… | 3 | ||
The Forward-Deployed AI Research Engineer | B2B | Aemon is the first autonomous research engineer that delivers state-of-the-art solutions to your engineering problems. It generates, tests, and evolves thousands of approaches at machine speed to discover optimal solutio… | 3 | ||
Okta for Agents. | B2B | Agentic Fabriq is the single control plane for data permissioning throughout your entire organization across your AI and employees. Through Fabriq, any employee can tap into AI/agents with exactly the data and tools they… | 2 | ||
Automation for institutional-grade financial modeling in Excel | Fintech | Alt-X is building the Cursor for financial modeling in Excel, an Excel agent that you can actually trust. Private-market investing still runs on Excel. Every year, trillions of dollars in real estate and private-equit… | 2 | ||
Your software should build itself. | B2B | Human-assisted development should be for novel ideation, not routine maintenance, bug fixes or incremental updates. Approxima is bringing you that future with agents that can scope work, code, validate their fixes end-to… | 2 | ||
AI benchmarks that measure general intelligence and inspire new ideas | Industrials | ARC Prize builds AI benchmarks that measure general intelligence. Our benchmark, ARC-AGI, has been used by OpenAI, Anthropic, Google DeepMind, and xAI. Founded by Mike Knoop and Francois Chollet, we inspire open sourc… | 4 | ||
Automated Multi-Modal Testing for Agents | B2B | Ashr is a fully contained test and evals platform that improves AI agents by ensuring accuracy and quality across a wide range of user journeys through your product. Ashr generates user journeys through your agents’ t… | 2 | ||
Real-world human movement data for humanoid robots | Industrials | Asimov collects real-world human movement data from households and businesses to train humanoid robots. Unlike factory datasets that capture the same tasks in the same environments, we deliver the full diversity of real … | 3 | ||
Claude code for Mechanical Engineers | B2B | There are 2 problems: The first, CAD software is slow and the second, designing with it is a tedious process with many steps. Aurorin solves both of these problems by being a CAD software built from the ground up on a… | 1 | ||
AI-native workspace for development plan reviews | B2B | At AutoSitu, we’re building coordinated AI agents that live inside cities’ cross-department development review workflows—doing the heavy lifting, escalating judgment calls, and letting staff focus where human expertise a… | 2 | ||
Stalk your prospects at scale. | B2B | Autumn is building the first real-time signal intelligence platform for GTM teams. We monitor posts, commits, blogs, and announcements, surfacing buying signals the moment they appear. Define your ICP and the signals tha… | 2 | ||
Harvey for Architecture | B2B | Avoice is an AI-native workspace for architecture firms that automates the non-design work that takes time away from design. The platform uses AI agents that understand drawings, specifications, schedules, materials, cod… | 4 | ||
Foundation models for 24/7 Earth Observation | Industrials | AxionOrbital Space builds foundation models that enable continuous visibility through clouds and darkness. Legacy optical satellites are rendered useless 70% of the time by weather and night cycles, while Synthetic Apert… | 2 | ||
An AI Copilot for Trading Desks | Fintech | Axis is building an AI Native Trading System, allowing a trader to deploy models that monitor and analyze relevant markets and strategies. We've chosen commodities as our first market. Commodities make up a third of glo… | 2 | ||
Full-Stack AI Accounting | B2B | Balance is an AI accounting firm that helps SMBs close their monthly books. Our agents do the work of an in-house finance hire, reconciling books in real time and flagging issues before they become problems. | 4 | ||
Detect what AI can automate for your team | B2B | Most teams want to plug in AI but don't know where to get started. BaseFrame's desktop app finds exactly what to automate for each employee using the historic data on their computer. Instead of relying on screen reco… | 2 | ||
AI Employees for Primary Care | Healthcare | Beacon Health (YC W26) is building AI employees that double revenue for primary care practices while also reducing the total cost of care. Primary care is the primary source of care for over 200M Americans, but physic… | 2 | ||
Frontier AI Defenses for Social Engineering Attacks | B2B | BeeSafe AI is building the frontier model layer for social engineering defense. Cyberattacks have moved from code to conversation: attackers now use AI to carry out long-term, trust-based manipulation across SMS, voice, … | 3 | ||
Space solar arrays that grow to the size of a football field in orbit | Industrials | At Beyond Reach Labs we are building solar panels for Space that grow from the size of a dining table to a football field in orbit. Mitch and Pele met 13 years ago as freshmen at UPenn studying mechanical engineering.… | 2 | ||
AI Electrical Estimator | Real Estate and Construction | We use AI to help electrical contractors submit more competitive bids to construction projects. We do this by speeding up the estimating part of bidding, which is the most tedious part of the job. Specifically, we're bui… | 2 | ||
Dynamically pricing the whole economy. | B2B | Booko helps businesses that sell bookable time slots make more money by dynamically pricing their time. Unlike physical inventory, unsold time slots disappear forever, yet most time-slot-based businesses still rely on st… | 2 | ||
Prompt once, automate forever. | B2B | Bubble Lab turns natural language into visual, production-ready workflows — built for modern ops teams, with built-in observability, logs, and execution traces. Deploy to Slack in one click so your team can build and … | 2 | ||
AI teammates for logistics | B2B | We're building for the people that keep the world moving. Freight brokers and forwarders operate on razor-thin margins in a relationship-driven business — yet most of their teams spend the majority of their day on ma… | 2 | ||
Button is the wearable AI that can talk. | B2B | We’re launching a small hardware device: a button that you clip to your shirt. You press it to talk to AI, and it responds instantly. | 1 | ||
Global upload acceleration for 1GB-100TB files. | B2B | Founded in 2025, Byteport is a technology company that builds mission-critical network infrastructure for robotics, satellite, AI, and enterprise applications all over the world. Businesses of every size—from new startup… | 2 | ||
Scaling formal verification to accelerate scientific discovery | B2B | Cajal (YC W26) is massively scaling formal verification to accelerate scientific discovery. We deploy superhuman AI mathematicians to high-impact applied domains, starting with quantum computing and finance. We do thi… | 2 | ||
The first AI QA engineer that understands your code | B2B | AI coding tools have made developers 100x faster but customer-facing incidents are up 43% YoY, QA hasn't kept up. Canary is the first AI QA engineer that understands your codebase. Instead of relying on flaky DOM scrapin… | 2 | ||
Give AI agents accurate knowledge search that scales | B2B | Captain delivers the most accurate file search engine built for AI agents. We’ll index data from the sources folks already use like S3, SharePoint, and Google Drive, and easily scale multimodal, petabyte-level content se… | 2 | ||
Agentic video editor | B2B | Cardboard is an agentic video editor for growth/marketing teams and serious creators who need to ship videos consistently. Instead of agencies, long timelines, and infinite review cycles, teams give cardboard a footage +… | 2 | ||
AI Platform for Precision Outbound | B2B | Hey YC! We're Devi and Jianna - the founders of Cardinal. TL;DR: Cardinal is the AI platform for precision outbound. We run outbound for 40+ YC companies, like Mintlify, Greptile, and Luminai. The Problem “Spray… | — | ||
Realtime AI for Sales Calls | B2B | Caretta is a Sales Intelligence for revenue teams. It joins reps in live calls, helping them handle information requests, questions, and objections in real time. Caretta lives in Slack to join the team conversation. C… | 4 | ||
Continuous Fine-Tuning for AI Models | B2B | We build specialized LLMs for your business’s specific workflows and use cases, then continuously hone them against your success metrics, capturing your proprietary know-how in the model so it gets more valuable and hard… | 2 | ||
Carson is a desktop AI app that generates custom, sharable workspaces | B2B | Carson is a desktop AI app that replaces the chat box by generating a custom, sharable workspace in seconds. Teams use Carson to collaborate with AI on their most important tasks, whether it’s processing insurance claims… | 4 | ||
Distilling Proprietary Intelligence | B2B | Cascade helps companies take their proprietary data and workflows to align models for their use cases, resulting in higher throughput intelligence that works better, faster, and cheaper. | 2 | ||
The most thrilling way to create and rip digital collectible packs | Consumer | CatchBack Cards is a mobile app and website platform for maximizing the thrill of collecting Pokemon and Sports cards. We allow collectors to create custom mystery packs with personalized chases and customized odds with … | 2 | ||
The agentic drug company. We simulate human biology. | Healthcare | CellType is building an agentic drug company. AI agents that run the full drug discovery pipeline on top of biological foundation models that simulate human biology. Our core technology, developed with Google DeepMind, h… | 2 | ||
The AIOps Agent for ML Teams | B2B | Chamber puts your AI infrastructure on autopilot, and saves your machine learning engineers hours of manual effort. Our agents continually monitor, detects failures, provide root-cause analysis, resolve issues, and optim… | 4 | ||
AI Revenue Engine for the Equipment Industry | B2B | Chasi deploys AI agents that help equipment dealers sell more, respond faster, and maximize fleet utilization - 24/7. One-third of the cost to build and maintain the physical world goes to equipment, yet fleet utiliza… | 2 | ||
AI automated prior-auths for private medical practices | Healthcare | We automate the entire end-to-end prior-authorization process for private practices for cheaper, and more accurately than they're doing today. | 1 | ||
Anyone can create real games with AI | Consumer | CodeWisp lets anyone build and publish web games using plain-English prompts. Traditional game development requires learning complex engines, managing assets and code, and following rigid workflows, making it slow and… | 3 | ||
AI automations that implement themselves | B2B | Cofia learns how your team runs internal operations and automates the highest-ROI workflows, automatically. | 2 | ||
LLM context compression for better accuracy | B2B | Compresr provides an API that compresses LLM context without losing what matters. It’s a drop-in for agents and RAG that cuts token costs and improves accuracy. | 4 | ||
Software for enterprise energy procurement. | Industrials | Condor helps large electricity consumers - C&I and data centers - cut electricity costs by helping the grid. We are former electricity traders and energy physicists. We build an AI-powered software that our clients use … | 3 | ||
AI models that learn from experience | B2B | While modern AI excels in any area you can collect a lot of data for, it struggles in areas where data is sparse or costly to attain. Designing new molecules, discovering new physics, and engineering new materials are al… | 2 | ||
AI native radars for self-driving cars | Industrials | At Congruent, we build radars for end-to-end autonomous systems. The most advanced autonomous systems are trained as a single neural network from raw sensor data to navigation actions. For a sensor to be included in thes… | 1 | ||
AI operating system for mega-scale satellite networks. | B2B | Constellation Space is building the autonomous infrastructure layer for the next generation of space networking. As satellite constellations rapidly scale from hundreds of nodes to tens of thousands, traditional ground-b… | 4 | ||
Agentic Mortgage Origination | B2B | Copperlane helps mortgage lenders accelerate the loan process and reduce mistakes in an application. We use AI agents to understand an applicant's profile, verify their documents, and complete initial underwriting tasks. | 2 | ||
AI on-call engineer for data-heavy, regulated industries | B2B | We’re building the AI on-call engineer for data-heavy, regulated industries like finance, healthcare, and insurance. Engineers in these industries need to inspect data to debug production issues. We continuously monit… | 3 | ||
AI agent workforce for CPG back-office | B2B | Corvera (YC W26) is the AI agent workforce for CPG back-office. We help brands increase profits by up to 40% by deploying digital workers that run their operations on autopilot. As of mid-March 2026, we scaled from $0… | 4 | ||
Protect, monitor and defend your Internet presence | B2B | Crosslayer Labs detects impersonation attacks on websites and APIs. We provide "outside-in" monitoring of customer infrastructure, comprehensively discovering and monitoring all Internet dependencies, including DNS, BGP,… | 3 | ||
Let users control your app through chat | B2B | Crow lets users control your app through chat. Connect Crow's AI agent to your product, and users can type what they want instead of clicking through menus. Crow connects to your APIs and data sources, navigates your … | 2 | ||
The Fastest Multimodal Inference OS | B2B | Cumulus Labs is a fast multimodal inference provider, purpose-built for AI teams who want faster performance, lower costs, and zero infrastructure work on fine-tuned & open source models. Most teams today are stuck ch… | 2 | ||
Tankless Dive Gear - Breath Autonomy at Sea, Land & Space | Industrials | DAIVIN! builds tankless dive gear that unlocks breath autonomy in extreme environments. Starting from underwater environment our mission is to remove the need for dangerous, heavy and bulky oxygen tanks in space, air and… | 1 | ||
Infrastructure for identity and fraud. | B2B | One API for KYC, KYB, AML, biometrics, and fraud — powered by 1,000+ data sources, 200+ signals, and in-house AI models. Global coverage. Integrate in minutes, pay as you go, 500 free checks/month. Start free at business… | 12 | ||
Evolutionary intelligence for autoimmune disease | Healthcare | Ditto Bio discovers drugs for autoimmune diseases by harnessing parasite biology. Viruses, ticks, and worms have experimented over millions of years to create proteins that control the human immune system. We use AI to i… | 3 | ||
AI-Native Med-Legal Firm | Healthcare | Docura Health reduces settlement time in workers’ compensation cases by automating medical record review, chronologies, and report drafting with AI. We transform thousands of pages of records into structured, compliant s… | 3 | ||
Doomscroll to learn languages | Consumer | Doomersion (formerly Doomlingo) lets you learn languages by doomsrolling! Watch TikToks in your target language that are exactly matched to your level, and as you scroll, they get a little bit harder. Gen-Z doomscroll… | 4 | ||
AI Document Workflows for Enterprises | B2B | EigenPal.com automates your document processing workflows with AI. KYC docs, invoices, claims, shipping forms, contracts, receipts, loan docs - we automate that. Works on messy scans, handwritten forms, third-party docs.… | — | ||
Open-source Agentic Development Environment | B2B | Agent-first development environment. Emdash enables engineering teams to develop software faster, by running multiple coding agents in parallel. We're an open-source and provider-agnostic desktop application. | 2 | ||
AI powered reconciliation for high-volume payments companies | B2B | End Close builds automatic reconciliation for payments companies like fintechs, marketplaces, banks and payroll companies. Reconciliation helps companies track every dollar and resolve every exception, ensuring they have… | 2 | ||
Interpretability and reasoning infra for foundation models. | B2B | Envariant is an AI interpretability and reasoning SDK enabling foundation model builders to analyze, steer, and control their model's behaviors. | 1 | ||
Autonomous OS for healthcare | Healthcare | Eos helps clinics turn their data into actionable insights to identify more eligible patients and early care interventions. We harmonize historical data across all systems to create standardized patient data distribut… | 2 | ||
AI agents that replace your policy consultants | B2B | Fed10 is a legislative consulting firm staffed by AI agents. We monitor every bill across the U.S., flag threats to your business, and deliver actionable insights — the same work a $500/hr policy consultant does, but… | 3 | ||
AI agents for banking back office | Fintech | We're building the Harvey for traditional financial services, starting with compliance use cases for small- to mid-sized banks in the US. Specialized AI agents for banks to 10x back office functions, which helps them … | 2 | ||
Enabling physical AI at scale. | B2B | Enabling physical AI at scale. | 2 | ||
An AI-first CRM built for Startups | B2B | Fixture is an AI-native CRM built for startups. It integrates with all the tools you use to communicate with customers, tracks marketing channels (e.g. website traffic), and pulls everything into a single go-to-market co… | 5 | ||
Keeping contractors on the job site, not behind a desk. | Real Estate and Construction | Foreman is the all-in-one AI-powered project management platform built for construction contractors and the trade industry. Today, contractors run complex businesses on a patchwork of tools that were never designed for … | 2 | ||
Strength Tracking Wearable | Consumer | Fort is a wearable that tracks strength training for people who care about longevity. Other wearables make you manually log every rep, set, and exercise, then provide unhelpful feedback or underestimate strength-related … | 3 | ||
The first regulated exchange to trade on attention. | Fintech | Forum is building the first regulated exchange to trade on cultural attention. We create indices from search, social, and streaming data to measure what the world cares about, enabling users to go long or short on cha… | 2 | ||
AI agents for corporate accounting teams | B2B | FullSeam builds agents for corporate accounting. Our agents replace manual accounting tasks that typically happen outside of our customers’ accounting software, like accounts payable, accounts receivable, and reconciliat… | 3 | ||
Moon Hotel -> The Intergalactic Construction Company of Earth | Industrials | GRU Space is building permanent lunar infrastructure to make humanity interplanetary within our lifetime, starting with the first hotel on the Moon. In just 6 weeks, we built the world's first Moon factory: patent-pendin… | 1 | ||
Robotics for Space R&D | Industrials | Robots for microgravity research and manufacturing. | 2 | ||
The AI native law firm for growth stage companies | B2B | We're the AI native law firm that solves commercial legal for founders. Our firm provides fast, high-quality contract drafting, review, and negotiation for a flat fee. We save founders $100s-$1000s per contract, turn con… | 15 | ||
The Interface Design Canvas for AI agents | B2B | Glue is an open source design editor for AI agents. It gives coding agents an infinite canvas to create new interfaces, iterate on existing ones, and turn those changes into production-ready code all in real time. The… | 2 | ||
API for performance-based payroll | Fintech | Grade is the API for performance-based payroll. Think of us like Deel or Gusto, but our payouts are for work completed, not hours. Companies use Grade to pay AI agents and contractors based on results: tasks completed, t… | 2 | ||
Robot Cowboys that Herd Cattle with AI Drones | Industrials | GrazeMate builds autonomous drones that herd cattle. On command, our drones fly to a paddock, position themselves around the mob, and move them where they need to go. What used to take a full day of helicopters, motor… | 3 | ||
Building Operational Superintelligence. | B2B | Haladir is the operational AI layer for logistics. We unify and structure data across WMS, TMS, OMS, etc., and embed solver-grade optimization, ML models, RL environments for frontier AI labs, and forecasting into the de… | 4 | ||
Agentic Offensive Security at Scale | B2B | Hex Security builds AI agents that run continuous penetration tests against your apps and infrastructure. Instead of a once-a-year penetration test, Hex Security's agents works 24/7 to find and verify critical vulnerabil… | 3 | ||
US-Made Parts for Robots | Industrials | HLabs is making an industrial supply chain for building robots in the USA including electronics and actuators, with a focus on in-house manufacturing. Robotics is going to be one of the largest industries the world ha… | 1 | ||
Multimodal data provider for robotics and world modeling | Industrials | We’re archiving the physical world for embodied intelligence by collecting and labeling aligned multimodal data. To build dexterous and perceptive robots that generalize robustly, we need massive amounts of real-world da… | 4 | ||
AI SRE agent that triages, coordinates, and fixes production incidents | B2B | AI SRE agents that automatically learn each customer’s system so they work just like an in-house engineer. | 2 | ||
We automate the inventory process in insurance | B2B | We automate inventory and contents processing for insurance and insurance-adjacent industries, including public adjusters, restoration contents, and insurance companies. We also handle various inventory and estimate adja… | 1 | ||
Real-time Physics Simulations for Industrial Facilities & Data Centers | Industrials | Inviscid AI builds physics-informed AI solutions that transform how buildings and data centers operate. By combining real-time IoT sensor data with computational fluid dynamics (CFD) modeling, we create digital twins tha… | 2 | ||
Automate enterprise workflows through chat | B2B | Jinba lets enterprise teams vibe-code AI workflows instead of drag and drop. Describe what you need in plain language, and your whole company can start using it immediately. No engineers required. Enterprise-grade permis… | 2 | ||
Automate credit review for lenders in emerging markets | Fintech | In emerging markets, open finance is still nascent. Most of the population is traditionally unbanked, banking APIs don’t exist, and a borrower’s financial history lives in documents: e-wallet records, bank statements, ut… | 2 | ||
Fast and Safe OpenClaw on the cloud | B2B | Get your personal OpenClaw instance on the cloud and connected to your Slack or other messaging app in 3 minutes. Pre-installed security features and common skills. | 2 | ||
Custom Aerospace-Grade Battery Packs | Industrials | Kyten Technologies is building a factory to manufacture custom aerospace-grade battery packs. 100,000+ drones, submarines, and satellites are being built in the US, but the legacy supply chain can't keep up. During o… | 2 | ||
AI Agents That Run Hotel Operations. | B2B | Autonomous AI agents that answer calls, close sales, and run operations, so your team can focus on guests. Trusted by some of the top hotel groups in the US, supporting 50+ hotels across brands like Marriott, Hilton, and… | 3 | ||
Autonomous performance marketing | B2B | Advertising today is like trading in the 1980s pits: archaic, manual, and iterative guesswork. Humans update bids and keywords using noisy, delayed data with fixed rules that both break at scale and ignore stochasticity.… | 2 | ||
The AI-Native Immigration Law Firm | B2B | LegalOS is an AI-native immigration law firm that combines cutting-edge technology with 40+ years of legal expertise. We’ve studied 12,000 successful petitions to design our process - which allows us to deliver top-qu… | 3 | ||
AI for Corporate Security Cameras | B2B | Lexius turns existing security cameras into an AI security guard that detects, documents, and alerts incidents like shoplifting and slip-and-falls. Millions of locations already have cameras but no intelligence. Repla… | 3 | ||
AI that understands human culture | B2B | Backed by top engineers from OpenAI, Scale AI, and Palantir to build AI that understands human culture. Our first commercial product is for the literature industry with a focus on school libraries. It the AI-native OS… | 3 | ||
AI that automatically improves products from user behavior | B2B | Lucent is an AI product manager that automatically improves products based on how users behave. We use AI to watch and understand user sessions and detect bugs and UX issues. | 2 | ||
Turning everyday words and actions into usable training data. | B2B | Luel is a sourcing and licensing platform for rights-cleared multimodal training data at scale. We work with frontier AI teams to provide high-quality bespoke data collections and off-the-shelf datasets. | 2 | ||
Foundation models for planning orthopedic surgery | Healthcare | Mango Medical builds agentic surgical planning AI for orthopedic surgery. We deliver surgeon-ready plans in minutes instead of days. 8-figure LOI from a top orthopedic company. Pursuing FDA 510(k) clearance. We're buildi… | 3 | ||
Digital Twins of humans | B2B | Mantis is a digital twin company that combines LLMs with high-fidelity physics simulations in order to convert rare and difficult-to-access human behavior data into predictive models. | 3 | ||
AI Video Production for Professionals | B2B | Martini is a collaborative, AI-native platform for professional filmmaking in the era of generative media. By integrating the best generative models into professional workflows, we enable world-class creatives to harnes… | 2 | ||
Payments Infrastructure for Voice Agents | B2B | We enable AI voice agents to collect payments over the phone through a single API call, handling card processing and PCI compliance across all payment gateways | 2 | ||
Automating the entire IB deal workflow | Fintech | Maywood automates deal execution for investment banks, from decks to diligence The Maywood platform automatically generates finished, on-brand CIMs / presentations, models, and diligence responses that prioritizes edi… | 3 | ||
AI DevOps Engineer | B2B | Mendral is an AI DevOps Engineer that observes, diagnoses, acts, and learns continuously. It autonomously handles CI failures, flaky tests, slow builds, broken releases, and code reviews, improving with every build and r… | 2 | ||
The AI data analyst for consumer brands | B2B | Menza is the AI data analyst for consumer brands. A brand like Hershey’s would connect all of their data sources and then we give them an AI analyst that works 24/7 looking for revenue opportunities, cost leaks, trends a… | 3 | ||
Technology to detect and track small drones | Industrials | We make radars that can see small drones. As drones evolve faster than air defenses, detection has fallen behind. Even $50 drones now present a major threat to airports, critical infrastructure, and front-line defense… | 3 | ||
Agentic Management Service for Care Organizations | B2B | MochaCare is an agentic management service for care organizations. We handle hiring, scheduling, and client intake end-to-end so our partners can focus on growth. | 2 | ||
The monitoring layer your AI agents need. | B2B | Moda is the reliability & monitoring layer for agents. It surfaces patterns across agent hallucinations, laziness, forgetfulness, and tool call failures. While also providing analytics on user frustration, net promoter s… | 2 | ||
Global AI-native law firm handling legal work with same-day turnaround | B2B | Moritz is a global AI-native law firm that will handle your legal work the same day, at a fraction of the market price. Our AI does 80% of the work, so you pay our elite lawyers for the final 20%. Our lawyers have … | 10 | ||
AI-powered fraud investigations | B2B | MouseCat enables companies to automatically detect, investigate, and mitigate emerging fraud trends | 2 | ||
Building AGI that can innovate. | Industrials | Ndea is building frontier AI systems that blend intuitive pattern recognition and formal reasoning into a unified architecture. # AI for Scientific Advancement Unlike all life before us, humanity's ascent is a stor… | 15 | ||
The AI Agent Inside Every Enterprise App | B2B | o11 integrates directly inside of Microsoft PowerPoint, Excel, and Word, along with Google Slides, Sheets, and Docs. We enable you to automate any workflow directly within these apps from crafting templated presentations… | 2 | ||
CV and robotics to automate quality inspection in fish farms | Industrials | OctaPulse uses AI vision to automate hatchery QA for fish farms, starting with broodstock phenotyping and juvenile deformity inspection. We cut inspection time from about 5 minutes to under 30 seconds per fish, with more… | 2 | ||
World models for robot evals and training. | Industrials | One Robot builds simulation environments that are realistic to see and realistic to interact with, so robotics teams can train and evaluate robot policies without being bottlenecked by robot time. Today, improving a V… | 2 | ||
Helping Healthcare Providers Speak Any Language | Healthcare | Opalite makes it easy for healthcare providers to communicate with non-English speaking patients. We’re built to work inside existing clinical workflows, so providers can communicate in real time without waiting for an i… | 3 | ||
Plan mode for complex features | B2B | OpenSpec is an open-source, spec-driven framework. We help developers plan complex features by creating lightweight spec documents that serve as durable context for their coding agents. With 20k+ GitHub stars, we’re o… | — | ||
Manipulate Anything Robot | Industrials | We are building a "manipulate anything" model with the robot hardware that embodies it. We designed a hand-based data-collection device and a high DOF, direct drive robotic hand that match each other exactly, enabling us… | 5 | ||
AI and Data for Cancer Therapeutics | Healthcare | Creating the largest patient-derived cancer single-cell dataset for licensing to pharmaceutical and AI companies. These datasets are unique as they screen the effects of various drugs and genetic medicines under the cont… | 4 | ||
Agentic Payments for APIs | B2B | APIs weren't built for agents. Orthogonal fixes that. We enable agentic payments so any agent can instantly discover, access, and pay for hundreds of APIs. No subscriptions, no sales calls, just pay per use. API provider… | 2 | ||
AI-Native Medical Billing Services | Healthcare | Overdrive Health offers AI powered medical billing services, helping providers get paid more money in less time. Our technology enables us to provide the best quality insurance and patient billing services for a fraction… | 1 | ||
AI Infra for real-time vision applications | B2B | Overshoot makes it easy for developers to build and run real-time vision applications. AI can see and understand the physical world. This unlocks new applications in physical security, safety, gaming, robotics and gen… | 5 | ||
See and control all AI activity across your enterprise | B2B | Oximy helps enterprises understand and manage AI usage across their workforce. Used by security, finance, and transformation teams to track adoption, control spend, and manage governance as AI scales. | 4 | ||
AI-powered automation for internal audit workflows | B2B | Oxus automates internal audits for pre-IPO and public companies using AI. Companies including leading payroll providers and public biotech companies work with us to streamline audit workflows and get audits done 10x fast… | 3 | ||
40% higher yields on company cash, in under 5 minutes. | Fintech | Palus Finance is the first treasury management platform with a higher-yield bond portfolio for companies’ idle cash. We launched in late February and are live with 33 companies, growing 110% week-over-week. Existing s… | 2 | ||
AI Native Commercial Insurance Brokerage | Fintech | Panta is a technology-enabled commercial insurance brokerage: we combine AI-powered internal workflows with licensed brokers to help businesses secure complex coverage faster than anyone in the world. | 3 | ||
AI front & back office agent for dental practices | Healthcare | Patientdesk is an AI bookings system that helps healthcare practices make more money. We do this by handling bookings, payments, and insurance to fill up a provider's calendar with high value appointments. | 5 | ||
The first AI-powered grand strategy platform | Consumer | Pax Historia is an alternate-history sandbox game where players choose a country, a moment in time, and rewrite the course of history. What if Rome never fell? What if the Soviet Union survived? What if Genghis Khan rule… | 3 | ||
AI Licensing Agent for Regulated Industries | B2B | Payna is building the AI licensing agent for regulated companies. We automate the filings, renewals, amendments, and regulator follow ups required to get licensed and stay licensed across jurisdictions, so teams no longe… | 2 | ||
The AI-native Recruiting OS | B2B | Perfectly is the first AI-native Recruiting OS. Since starting YC, we’re already helping top startups like Giga, Corgi, LlamaIndex, Porter, and dozens more hire faster. We’re seeing: -> 4× faster hiring -> 10× ca… | 3 | ||
Inference at Light Speed | B2B | Piris Labs offers a full-stack inference service that eliminates the AI data movement bottleneck. By pairing proprietary photonic hardware with a vertically optimized software stack, we minimize the "memory wall" associa… | 4 | ||
Take Notes in the Real World | Consumer | Pocket is a small AI device that turns everything you say and hear into clear notes, action items, and search. We combine custom hardware, AI, and software to build the best note-taking experience for people who talk and… | 6 | ||
AI agents that automate customer success | B2B | Pollen is building AI agents that autonomously improve retention. Pollen monitors every customer account to detect back-tested churn and upsell signals by connecting to your communications, support tickets, product usage… | 3 | ||
AI Agents for the supply chain. | B2B | Supply chains still run on spreadsheets and inboxes because ERPs are rigid and the data is messy. We're solving this problem by building an ontology where agents can operate and provide outcomes for our customers. We … | 2 | ||
Simulation environments to train & evaluate long-horizon AI agents | B2B | We’re heading towards a future where AI agents will be able to perform useful work over long horizons, with little or no human supervision. To increase the reliability, performance, and safety of autonomous agents, they … | 2 | ||
Personalization infra that improves retention, LTV, and CAC | B2B | Polymorph is personalization infra that lets developers use AI to personalize their apps, improving conversion, LTV, and CAC for consumer and self-serve apps. This infra is used to personalize user experiences and not… | 3 | ||
An AI primary care doctor in your pocket | Healthcare | Prana replaces the reactive, 15-minute annual physical with continuous, proactive care. We connect to your medical records and wearables to watch for "clinical drift," catching subtle declines in health that human doctor… | 4 | ||
Real time intelligence for law enforcement & security teams. | B2B | We provide real-time video intelligence that identifies escalating incidents as they unfold. Protent detects early escalation patterns and predictive threat signals, giving security teams the immediate context they need … | 2 | ||
AI operating system for commercial loans | Fintech | Proximitty is the AI operating system for commercial loans - we build regulator-grade AI agents that ingest and parse documents, spread financials, automate loan operations and track covenants. We help FDIC-insured ba… | 2 | ||
We help private equity teams find acquisition targets faster | B2B | Q2Q is the AI-native outbound engine for deal sourcing. Tell us the types of companies you want to buy, and we'll get qualified meetings booked for you. You can think of Q2Q as your personal team of AI interns. You g… | 2 | ||
Automate any UI task with natural language | B2B | RamAIn can intelligently automate any super complex and repetitive process across applications (Browser & Desktop) super fast. It doesn’t matter whether you have API access or not - if you can see it, RamAIn can do it. … | 4 | ||
AI-native, hardware procurement marketplace | B2B | Reframe is the only AI-native marketplace for hardware teams to procure both COTS and custom manufactured components. We have access to trusted suppliers that have made parts for the most reliable hardware products that … | 1 | ||
Social media content auto-generated with your existing data | Consumer | Remix is the easiest way to create content with AI. Connect your accounts, drop in photos, voice notes, or messages, and Remix instantly creates posts in your style: articles, tweets, carousels, short-form videos, even c… | — | ||
Computer vision for smarter & safer warehouses | Industrials | Warehousing is a $500B industry in the US, and 90% of its operators already have security cameras installed. Yet fewer than 10% use them for anything beyond security. Meanwhile decision-makers sit in their offices all da… | 2 | ||
AI Workers for Field Services | B2B | We automate the back office so field crews can focus on the actual work. Trades businesses (HVAC, plumbing, electrical, collision repair, roofing) run on legacy software and "glue" employees: people whose entire job i… | 4 | ||
Claude Code for Mechanical Engineers | B2B | REV1 is Claude code for mechanical engineers, starting with automating the process of turning 3D designs into 2D manufacturing drawings – which is more than 25% of all of what a mechanical engineer does - our software do… | 2 | ||
Intelligence for Automotive Operations | B2B | Revion is building the operating system for Automotive Retail. Our first product helps Technicians automate administrative work, which drains 30-40% of their day. With Revion, Auto Retailers can service more vehicles and… | 4 | ||
Agent Platform for Life Sciences | B2B | It takes 500,000 days of office work to bring a drug to market. We want to make it 5. To get there, we need agents doing most of the work. Today, our research agent is the best way to know what the FDA thinks. Users … | 1 | ||
AI-native platform for Life-Sciences Documentation | Healthcare | Ritivel is an AI-native workspace for regulatory and medical writing teams at life sciences companies. Our AI agents draft CTDs, CSRs, INDs, and BLAs in minutes instead of weeks, helping drugs reach patients faster. E… | 3 | ||
AI agents that grow revenue for home services businesses | B2B | Robby is an AI growth engine for home services businesses that uncovers revenue opportunities and collects additional data from every technician visit. Our AI combines customer and third party data to generate dozens of … | 3 | ||
Robots that run autonomous depots for autonomous fleets. | Industrials | RoboDock builds robots that automate depot operations, like charging and vehicle checks, for electric and autonomous vehicle fleets. We turn fleet depots from manual sites into self-running systems that lower operational… | 2 | ||
Reasoning and verification infra for AI | B2B | Rubric AI (backed by Y Combinator) is the reasoning and verification infrastructure for AI. We're building the human and computational layer that turns expert judgment into training signals for the world's most consequen… | 2 | ||
The operations stack for biologic infusion clinics | Healthcare | Ruma Care automates all admin work for infusion clinics - starting with prior authorizations & copay assistance enrollment. Biologics are expensive medications that cost $80-$150K+ per year per patient, and often need… | 2 | ||
The default way of running on-device AI at Scale | B2B | Edge AI is inevitable, but shipping it is painful: every device class behaves differently, runtimes vary, models are huge, and performance collapses under memory/power constraints. RunAnywhere turns that into an enterpri… | 2 | ||
Guardrails to validate your agent's actions before they execute | B2B | Your agent processed a refund without looking up the order ID, costing you thousands. You only found out three hours later from a support ticket. Evals, output scoring, and observability can reduce the likelihood of mist… | 2 | ||
Multilingual voice agents that outperform humans | B2B | Samora runs multilingual voice operations for organizations with high-volume calling without requiring engineering teams, call centers, or AI expertise. Many important tasks still depend on phone calls, including cust… | 8 | ||
Logistics infrastructure to modernize healthcare operations | Healthcare | Scheduling Wizard is building the logistics infrastructure to modernize healthcare operations. Hospitals still rely on manual workflows to manage staffing, patient flow, and core operations, contributing to $760B in annu… | 3 | ||
Modular AI-Commanded Drones for Defence | Industrials | We engineer inexpensive, autonomous strike drones designed to operate in the most contested combat environments on Earth! By combining true hardware modularity with an agentic control system that lowers cognitive load… | 2 | ||
Datadog for Agent Reliability | B2B | Sentrial is the monitoring platform for AI products in production. When your AI product/agent loops indefinitely, hallucinates, or frustrates users, Sentrial detects it in real-time, diagnoses the root cause, and rec… | 2 | ||
Low-latency execution across crypto, prediction, and tokenized assets | Fintech | Sequence Markets lets traders execute across crypto exchanges, prediction markets, and tokenized-asset venues from one system. We built proprietary low-latency infrastructure and routing software so users can package … | 5 | ||
Robots that 10x manual industry work | Industrials | You’re wasting millions of dollars on custom industry robots that take months to implement. Today, robotic automation means redesigning your entire facility for the robot to work. You need to change the floor plan, ad… | — | ||
The World's Largest Video Library | B2B | We are building the world’s largest video library. We've aggregated billions of videos into a searchable index and use agents to find and label the exact datasets a lab needs on demand. If a lab needs 100K hours of co… | 4 | ||
Media infra for consumer apps | B2B | ShortKit lets any consumer app launch a TikTok-grade media expereinces. Michael, spent 6 years at YouTube building the infrastructure that powers YouTube Shorts. Neil, prev. scaled a SaaS company from 0 to $6M ARR as… | 2 | ||
Proactive AI customer support that engages high-value users | B2B | Proactive AI customer support that engages high-value users. By using LLM’s to engage customers in an authentic way before they reach out to customer support we minimize support tickets, build relationships and deliver u… | 2 | ||
Agentic Workplace Messaging | B2B | Every great company in history was built on one thing: communication. Sila is an agentic workspace messaging & collaboration platform where teams and AI work as one. Our mission is to lead the future where human-AI commu… | 2 | ||
Marketing suite for the agentic web | B2B | sitefire (YC W26) helps brands market their products to agents. They create content and tools that get their products discovered and used by AI agents (ChatGPT, OpenClaw). sitefire identifies which content drives AI visi… | 2 | ||
Hire engineers based on what they’ve shipped | B2B | Skillsync is an AI recruiter that hires engineers based on what they've shipped. The best engineers are not on LinkedIn. They're on GitHub, busy shipping code. But GitHub is massive, chaotic, and nobody had made it searc… | 2 | ||
Makes software self-healing | B2B | We want software to improve itself. Sonarly connects to your monitoring stack - tools like Sentry, Datadog, and Grafana - and triages every alert to remove noise and duplicates. It then investigates logs, traces, metr… | 2 | ||
Make everyone on your team an engineer | B2B | Sparkles is like Lovable for existing projects, so even Sharon from Marketing can change the button styling on the front page without going back and forth with the dev team. Someone technical connects their GitHub to … | 1 | ||
Financial infrastructure for the agent economy | B2B | Sponge is the easiest way for agents to hold and spend money, and for businesses to sell directly to them. For agents: Sponge lets agents hold funds and transact autonomously with other agents and businesses using ban… | 3 | ||
Stablecoin Global Bank Account | Fintech | SpotPay is a global borderless neobank. We give users one account that works for everything payments related: receiving money from abroad, paying locally, spending anywhere with the SpotPay card and saving and earning on… | 2 | ||
AI agents for power grid planning 🦑 | Industrials | We believe the electricity grid is the most important machine on Earth. If we want electrification to move fast, the teams planning and operating networks need software that is as modern as the challenge. Our thesis i… | 2 | ||
Agentic AI for intellectual property | B2B | Stilta builds agentic AI software for intellectual property, starting with patent litigation. Whether challenging or enforcing a patent, leading IP law firms and in-house IP teams use Stilta for source-backed, auditable … | 4 | ||
Multimodal foundation models to predict uncollected patient biology | Healthcare | Strand AI develops foundation models to generate missing bio-data about patients. With this imputed data, pharmaceutical companies can select better patients for their drug trials and shave months from their drug launch … | 2 | ||
AI assistant for your email and calendar | B2B | Supafax is an AI agent that lives in your inbox and proactively manages your email and calendar. | 2 | ||
Claude Code for Scientific Research | B2B | We’re building the infrastructure for the future AI co-scientist, starting with computational research. Our core thesis is that powerful AI scientists require two things built together: a human-centered product that gene… | 2 | ||
The agentic coding app for complex tasks. | B2B | Syntropy is an autonomous coding agent built for complex long-horizon tasks, that turns a feature description into a fully tested implementation. Instead of babysitting a terminal for hours writing prompts and managing c… | 2 | ||
AI for AI Infrastructure | B2B | We deploy fleets of AI Infrastructure Engineers to collaborate over week-long time horizons, run 100s of experiments in parallel, and learn from them to optimize your training/ inference infrastructure to your workloads.… | 2 | ||
AI Employees for Startups, Built on OpenClaw | B2B | Tensol lets you deploy and manage AI employees for your team - built on OpenClaw. Your AI employee has full context of your company, is running 24/7 and can monitor Slack, track Sentry errors, update your CRM. We handle … | 2 | ||
AI-native operating system for aesthetics & wellness | B2B | Tepali is the AI-native operating system for medspas. We replace fragmented software and manual work with a single system of record powered by AI agents that handle front desk, patient documentation, and lead conversion. | 2 | ||
Vercel for background agents | B2B | Terminal Use is an orchestration platform for background agents. Purpose-built for agents that use filesystems. Our platform is CLI-first, making it easy for your coding agents to experiment and continuously improve your… | 4 | ||
The first AI-powered uranium discovery company | Industrials | Terranox is the first vertically integrated AI-powered uranium exploration company. We find high-grade uranium deposits in North America using AI trained on 70+ years of exploration outcomes. Our mission is to find the f… | 2 | ||
Compression middleware that improves LLM outputs | B2B | Compression middleware that removes context bloat in milliseconds, lowering costs and improving end-to-end latency. Compression is especially effective across natural language workloads. In a blind LLM arena case stud… | 2 | ||
Research lab for non-verifiable work | B2B | Public profile enrichment pending. | 1 | ||
The data infrastructure for real estate | Real Estate and Construction | We are building the most accurate and comprehensive real estate data set. Travo is the one stop shop for anyone working in real estate to search any property or parcel of land and instantly access rental comps, ownership… | 4 | ||
Multi-chain deposit and payment infrastructure | Fintech | Launch crypto deposits in minutes. Unifold is a developer-first API + SDK that makes it easy for any app to accept on-chain deposits – across any chain and token – with less than 10 lines of code. We handle the full … | 3 | ||
AI agents that automate B2B software implementation | B2B | Unisson is building trusted AI subject-matter experts for teams that are responsible for customer deployments (technical customer success, implementation, sales engineering). Within 20 minutes, our agents learn to use an… | 2 | ||
Unified prediction markets trading platform | Fintech | Valence is a unified trading platform for prediction markets. We provide infrastructure to aggregate and execute contracts across Kalshi, Polymarket, and other platforms, surface arbitrage and mispricing opportunities in… | 3 | ||
Insurance risk layer for physical AI | B2B | Insurers struggle to price autonomous systems because the historical data simply doesn't exist. Your car insurance draws from over 30 billion claims records, but autonomous trucks and robots have nearly zero. Valgo is th… | 3 | ||
Full service ai law firm & software solution, for startups | B2B | A modern solution for Startup legal: we are a premier, full service, hybrid AI law firm & legal tech platform. Customers get software + white glove lawyer support for maximum value on each legal matter. Services: … | 4 | ||
AI Agents For Complex Scheduling Coordination | B2B | We are building Vela, the AI scheduling assistant for the most complex interactions. Everyone assumes scheduling is a calendaring problem. It's not. It's a human nuance problem: knowing who to prioritize, how hard to pus… | 4 | ||
The OS for data quality across any stack | B2B | Velum is the operating system for data quality. Velum automatically monitors and enforces data quality across a company's data stack, so bad data never reaches dashboards. We turn data quality from a manual task into inf… | 2 | ||
AI Workforce for Distributors and Manufacturers | Industrials | Ventura builds the AI workforce for distributors and manufacturers, starting with quoting and order entry. It plugs into your existing ERP, follows your SOPs, and learns your team's tribal knowledge - getting smarter wit… | 2 | ||
AI Verification for Insurance | Fintech | Verdex is an AI insurance adjuster. We use data streams like satellite imagery to verify claims, allowing insurers to process it immediately and save billions of dollars. We are currently helping insure over 11% of all A… | 2 | ||
A faster, lower cost path to custom silicon | B2B | Visibl makes custom chip development dramatically faster and lower cost for hardware companies. Today, most hardware companies that need a custom chip have bad options: sign a massive contract with an incumbent like B… | 2 | ||
Autonomous Drones for Earth Observation | Industrials | Voltair is building the world's first globally distributed network of autonomous drones for Earth observation. Power utilities are the perfect first customer. Aging infrastructure and extreme weather drive the need fo… | 5 | ||
Energy independent data centers with solar and repurposed batteries. | Industrials | The best grid connection is no grid connection. Voxel builds vertically integrated energy generation and storage systems for data centers that bypass utility connection delays. By leveraging the vast supply of second… | 3 | ||
Real-world place intelligence for AI apps and agents | B2B | VOYGR is a better maps API every agent and AI app will need. Google says '4.2 stars, open till 10 – VOYGR knows the chef left, wait times doubled, and locals moved on. Our intelligent local search combines accurate place… | — | ||
AI operator for medlegal cases | B2B | Wayco is building a unified data intelligence layer for medical treatment of legal cases. From the first intake to instant settlement. | 1 | ||
AI coworker for video editors to ship more video faster | B2B | Wideframe is an AI coworker for video editors. It automates the searching, labeling, organizing, and sequencing of footage so editors can ship videos faster. Why is this important? Well, it turns out that editors spen… | 2 | ||
Turning all software into agent-first APIs | B2B | Public profile enrichment pending. | 3 | ||
Drop-in Direct Billing SDK for In-App Purchases | Fintech | ZeroSettle is a mobile SDK that switches customers from App Store billing to direct billing. It takes 15 minutes to set up and immediately unlocks zero App Store fees, higher retention/conversion, and instant payouts. | 2 | ||
Automates admin for aircraft mechanics | B2B | Public profile enrichment pending. | 3 |