YC Summer 2018 (S18) companies

64x Bio engineers high-yield cell lines and production technologies for gene and cell therapy manufacturers hitting manufacturing bottlenecks. Its VectorSelect platform combines massively parallelized screening with computational analysis to optimize viral vector and biologic production systems, covering AAV, lentiviral, and protein therapeutics. The work replaces slow, low-throughput cell line development that constrains the scale-up of advanced therapies.

Activeloop builds continual learning infrastructure for AI teams, centered on three products: Deep Lake, a GPU-native vector and tensor database for storing, versioning, and streaming multi-modal datasets; Hivemind, a shared memory layer that captures agent traces and distributes reusable skills across an organization; and Refinery, a software factory that converts production feedback into verified model and workflow improvements. The stack targets engineering teams running AI agents or fine-tuning models at scale, replacing ad-hoc data pipelines, scattered prompt logs, and manual retraining cycles.

Aesthetic builds an AI tool for creative professionals that learns a designer's personal visual style and generates on-brand imagery from that learned style. It replaces the manual work of producing style-consistent visuals from scratch, letting designers delegate routine image generation to a trained model rather than doing it by hand.

Ajaib builds a mobile brokerage platform for Indonesian retail investors, letting them trade Indonesian stocks, ETFs, mutual funds, bonds, crypto assets, and US equities in one app. It targets the large share of Indonesians who previously had no practical access to capital markets, replacing the paperwork and high minimums of traditional brokerages with a fully digital account-opening and trading experience.

Allotrope Medical builds an electrical stimulation platform that gives surgeons active control over smooth muscle tissues during surgery. Surgeons use it to locate structures such as ureters and sphincters, assess tissue health, and detect disease states that are otherwise hidden during a procedure. The technology integrates with existing surgical instruments, replacing the passive, visual-only methods surgeons have relied on for decades.

Alpha Vantage delivers financial market data APIs covering equities, ETFs, mutual funds, indices, forex, commodities, cryptocurrencies, economic indicators, and technical indicators. Developers, quantitative researchers, and enterprises use these REST APIs, MCP servers, and spreadsheet integrations to access real-time and historical market data without building or licensing their own data infrastructure. Alpha Vantage is NASDAQ's officially licensed US market data provider.

Anima App converts Figma designs, live websites, and images into clean React, HTML, or Vue code, serving product, design, and engineering teams. It replaces manual design-to-code handoff and front-end scaffolding by generating developer-ready output that preserves a team's existing brand and design system. Non-technical teammates can build and iterate directly without Figma skills, then hand off a working codebase or shareable link to engineers.

AnnieCannons trains survivors of human trafficking and gender-based violence to become professional software developers, replacing dependency on low-wage or exploitative work with careers in tech. The nonprofit pairs technical education with practical programming skills, giving graduates the tools to build software solutions to problems they have directly experienced. It serves a population that standard workforce pipelines routinely overlook.

Apprentice Health builds sensor-driven software that helps hospitals and clinics run clinical workflows more efficiently. It places ambient sensors throughout care settings to track patient and clinician movement in real time, then combines that data with scheduling optimization, simulation, and AI to reduce wait times and keep exam rooms utilized. The product replaces manual workflow observation and ad hoc scheduling adjustments made by operations and clinical leadership.

AskMyClass builds a voice-based learning assistant for K-12 classrooms, serving teachers and students through smart speakers such as Alexa. It handles classroom management, social-emotional learning, and lesson support, replacing the manual work teachers do to redirect off-task students and deliver structured instructional prompts.

Avo embeds a virtual marketplace inside residential and office buildings, letting tenants order groceries, cleaning services, and other consumer goods without leaving their building. Building operators bring in their tenants as customers, which cuts acquisition costs, and consolidated deliveries to a single address eliminate last-mile logistics fees. The model replaces fragmented retail and on-demand delivery apps for both property managers and residents.

Berbix builds ID verification and fraud detection software for online platforms that need to confirm their users' real-world identities. Companies integrate Berbix through developer-facing SDKs to automate the review of government-issued IDs, replacing manual checks or weaker self-attestation flows. The product targets any regulated or trust-sensitive platform where a fake or misrepresented identity creates meaningful risk.

BHRD builds investor communications tools for public companies. It handles the work of translating corporate updates and disclosures into messaging that reaches and engages shareholders. The product targets public company IR and communications teams who would otherwise manage that outreach manually.

BlueCargo builds an AI-powered freight audit and spend management platform for international supply chains. It serves global shippers, logistics service providers, and drayage carriers by automating the validation of ocean and drayage invoices against contracted rates and real-time port data, catching overcharges before payment and recovering them after. The product replaces manual back-office invoice review and dispute workflows across the procure-to-pay freight lifecycle.

Bot MD builds AI agents for hospitals and clinics that handle patient-facing communication across messaging channels including WhatsApp, LINE, Telegram, and SMS. The agents cover appointment booking, pre-admission intake, care follow-up, and routine patient inquiries, replacing work previously done by front-desk and care coordination staff. Deployments integrate with existing EMR, HIS, and queue management systems across Asia-Pacific.

BrainHi builds an AI-powered receptionist platform for healthcare providers, government agencies, and enterprise service teams. It handles inbound calls around the clock, books appointments, and answers routine administrative questions, replacing the manual phone work typically done by front-desk staff. Providers get back missed calls and scheduled appointments without adding headcount.

C16 Biosciences produces fermentation-derived oils and fats under its Palmless brand, replacing palm oil and other commodity-sourced ingredients in beauty, personal care, and food products. Its biomanufacturing platform lets consumer goods manufacturers swap in locally scalable, supply-chain-stable ingredients instead of imported commodities exposed to price swings, tariffs, and regulatory pressure. The lead product, Palmless Torula Oil, is a bioactive emollient positioned as a higher-performance substitute in formulations where conventional plant oils are used today.

Calii delivers fresh produce and grocery items to consumers in Latin America in under two hours, sourcing directly from producers and brands through a network of micro-fulfillment centers. By cutting out intermediaries across the food supply chain end-to-end, Calii replaces the traditional offline grocery run while reducing spoilage and food waste.

Canary Technologies builds a hospitality management platform that replaces paper-based front-desk and guest workflows with digital tools covering check-in, registration, upsells, messaging, contracts, payments, and AI-driven sales coordination. Hotels use it to run operations that previously depended on physical forms, manual authorizations, and in-person staff handoffs. Customers range from independent properties to large brands such as Four Seasons and Wyndham.

CB Therapeutics engineers yeast-based fermentation to produce cannabinoids, tryptamines, and other rare alkaloids at scale, replacing crop extraction and chemical synthesis as the supply route for these compounds. Its AI-guided biosynthetic platform spans eight compound classes, including phytocannabinoids, ergolines, and peptides, running each molecule through repeated design-build-test cycles to hit target purity and consistency. The company targets both therapeutic development, addressing conditions such as depression, PTSD, and opioid addiction, and commercial ingredient supply for wellness markets.

Circumvent develops precision medicines for neurodegenerative diseases, starting with Batten Disease, a rare fatal disorder. Research into Batten Disease has surfaced mechanistic insights into synaptic function, protein localization, lysosomal activity, and the palmitoylome, a set of lipid-modified proteins central to brain-cell health. Circumvent applies these findings across both rare and common neurodegenerative conditions, replacing the field's reliance on low-fidelity disease models with genetically defined, high-predictivity biology.

Clear Gene builds RNA diagnostic tools that detect residual solid tumor cancer after treatment, using genomics and machine learning to serve a patient population that liquid-tumor detection methods have historically not reached. Its MICA platform gives clinical labs a unified signal-processing interface and drop-in PCR reagents that replace fragmented interpretive software and time-intensive RNA isolation workflows. The company targets oncology and clinical diagnostics labs, removing manual, multi-instrument processes from sample preparation and result calling.

College Pulse builds survey research and analytics products that help businesses and nonprofit organizations understand the U.S. college student demographic. It operates a proprietary panel of college students and recent graduates drawn from two- and four-year institutions across all 50 states, replacing the slower, patchier fieldwork that traditional market research firms rely on. Clients can commission custom surveys, ongoing brand trackers, or buy syndicated reports.

Contrast builds a Storybook addon that automatically compares rendered UI components against their Figma designs, highlighting pixel-level differences in real time. It targets frontend developers on component-driven teams, replacing the manual cycle of toggling between browser DevTools, Figma, and QA checklists to verify that code matches spec. Design tokens and Figma files stay synced inside Storybook, so developers inspect spacing, variables, and linked stories without switching tabs.

Coral Genomics develops clinical laboratory tests that predict which treatments will work best for individual autoimmune disease patients. The tests combine molecular, functional, and clinical data to guide treatment decisions, replacing trial-and-error prescribing. The company also targets a distinct patient subpopulation that does not respond to existing autoimmune therapies, an area current diagnostics and treatments do not address.

Corvus Robotics builds autonomous drone systems that scan and track inventory inside warehouses, replacing manual cycle counts and the labor teams that perform them. Its drones fly indoors without operators, read shelf locations, and feed discrepancy data into warehouse operations. Customers include large distribution centers running millions of SKUs across multiple sites.

Cowrywise builds a savings and investment platform for retail consumers, high-net-worth individuals, and corporates in Nigeria. It gives users direct access to personal savings accounts, mutual funds, and stocks through a single app, replacing the friction and cost of traditional wealth management services. Licensed by Nigeria's SEC as a fund manager, it also offers an embed API that lets other apps plug investment services into their own products.

CSPA builds a standardized proficiency exam for software engineers, assessing technical knowledge across a broad range of computer science topics. Engineers take the test, and results are shared with employers and schools, replacing ad-hoc screening and unstructured technical interviews. Employers access a SaaS product to browse a database of scored candidates, while CSPA handles exam content, proctoring, and autograding.

Culdesac designs, builds, and manages residential neighborhoods built around walking, cycling, and transit rather than private cars and parking. Residents live in mixed-use communities that embed local retail, open space, and mobility partnerships directly into the neighborhood, replacing the need for a personal vehicle. The model targets urban renters who want connected, car-free living without sacrificing access to city amenities.

Curebase builds an AI-powered eClinical platform for biotechs, pharma companies, CROs, and research sites running clinical trials. It covers the full study lifecycle: recruitment, eConsent, electronic patient-reported outcomes, participant engagement, and data capture in a single integrated system. The platform replaces fragmented, legacy clinical trial software that slows study startup and produces messier data.

Data Driven Bioscience builds Duoseq, a cancer genomics platform that profiles tumor DNA and RNA simultaneously from a single sample and delivers a sequencing report in two days. It serves pathologists, oncologists, and biopharma teams, replacing multi-step, multi-vendor workflows that separate DNA and RNA analysis. Results are generated on-site and flow directly into EPIC and other EHR systems, cutting out external lab shipping and the delays that come with it.

Demeanor.co was a consumer media and advertising company that is now part of NTWRK (thentwrk.com). The current demeanor.co website has been taken over by an unrelated Thai-language content blog, so no product details can be drawn from it. The company's original work is reflected only through its acquisition by NTWRK.

Dinesafe crowdsources food safety incident reports from consumers and uses that data to detect and prevent foodborne illness outbreaks in real time. The platform serves public health agencies, food industry operators, and individual consumers, replacing slower, manual surveillance and reporting processes. By aggregating crowd-sourced signals, Dinesafe gives all three groups earlier visibility into emerging food safety risks.

dNovo develops a cellular reprogramming technology to generate new hair stem cells, targeting patients with hair loss caused by male-pattern baldness or age-related hair miniaturization. A small sample of a patient's skin or blood is converted into personalized hair stem cells that replace those lost, producing new hair rather than slowing its loss. Beyond hair, dNovo aims to apply the same platform to regenerate other cell types, tissues, and organs lost to aging.

Dorian Therapeutics develops therapeutics targeting the biology of cellular aging to treat age-related diseases and tissue decline. The company works on restoring the capacity of cells to resist the stressors that drive disease, replacing the conventional approach of treating symptoms after degeneration has occurred. Its focus is translating rejuvenation science into medicines for conditions rooted in aging.

DreamCraft Entertainment, Inc. builds a code-free game creation platform that lets people without programming or art skills design, publish, and monetize video games. The platform bundles a game editor with pre-made art assets, replacing the need for a professional development team or technical background. It targets aspiring and hobbyist game creators who would otherwise be blocked by the cost and complexity of traditional game development.

Duffel builds an API that lets any business sell travel, replacing the need for direct airline accreditation, ticketing authority, and custom integrations. Challenger banks, spend management platforms, and other non-travel companies use it to offer flight search, hotel booking, seat selection, and order management inside their own products. The work Duffel replaces is the years of infrastructure, accreditation, and supplier negotiations required to distribute travel inventory.

Easol builds an all-in-one commerce platform for experience creators, covering website design, booking, payments, marketing, CRM, and operations. It targets businesses that sell ticketed or bookable experiences, such as music events, adventure trips, and competitive socialising venues, replacing a patchwork of legacy tools and rigid third-party platforms. Creators sell directly through their own branded storefront rather than through intermediary marketplaces.

Eden builds AI infrastructure for medical imaging that converts diagnostic data into clinical answers for radiologists and physicians. Its platform processes imaging data and returns precise diagnostic outputs, replacing manual interpretation workflows. Eva Centers, located in shopping malls, deliver infrared-based breast cancer screening in under ten minutes without invasive procedures.

Embeddables builds HIPAA-compliant intake funnels for health and wellness brands, replacing generic form builders and custom engineering work. It handles the hard infrastructure underneath, including patient routing, pharmacy connections, and compliance, so non-technical teams can draft, launch, and iterate clinical intake flows without waiting on developers. Teams use a low-code editor or an AI-assisted CLI workflow to go from protocol to live funnel in days.

Enveritas verifies global supply chains for social and environmental compliance issues such as child labor and forced labor. It serves companies that source commodities internationally and need credible assurance that their supply chains meet ethical standards. The work it replaces is traditional, audit-heavy verification that is slow, costly, and difficult to scale across complex supplier networks.

ExceptionALLY connects parents of children with special needs to expert guidance on navigating education, therapies, and support services. It replaces the fragmented, expensive process of consulting specialists independently by making that expertise accessible and affordable in one place.

FameGame builds live, interactive game shows streamed directly to mobile phones, letting players compete in real time for prizes and recognition. The product targets everyday consumers seeking entertainment, replacing passive TV viewing with participatory, broadcast-style competition accessible from any smartphone.

Federacy delivers manual penetration testing and bug bounty programs to startups and growth-stage companies. Security researchers test web and mobile applications, APIs, and external network infrastructure against standards including OWASP ASVS, NIST SP 800-53A, and OSSTMM, replacing the patchwork of ad-hoc audits and compliance checkbox exercises those teams would otherwise manage themselves. The output satisfies SOC2, ISO 27001, and HIPAA requirements as well as enterprise vendor security assessments.

Fintual builds a regulated digital wealth manager for retail investors in Chile and Mexico. It offers mutual funds, retirement savings, stock trading, and low-risk cash reserves through a single app, replacing the paperwork and minimums that traditionally kept everyday savers out of investment products. Individuals and companies manage their own portfolios directly, without needing a traditional broker or financial advisor.

Four Growers builds robotic harvesting and analytics systems for commercial greenhouse growers of tomatoes, peppers, and cucumbers. Its robots navigate greenhouse rows, identify ripe produce using stereo cameras and proprietary decision-making algorithms, and handle harvesting, quality inspection, and storage, replacing manual picking labor. The company targets the full crop-management workflow, with patented hardware design and software controls as its technical foundation.

FREY makes premium, eco-conscious laundry and clothing care products, including liquid detergents, detergent sheets, dryer sheets, fabric softener, scent boosters, and stain removers. The products use plant-based formulations free of parabens, dyes, and toxic chemicals, targeting consumers who want effective cleaning with luxury scents and cleaner ingredients. For each bottle purchased, FREY washes the clothing of someone in need through its Wash for Wash program.

Gerostate Alpha develops therapeutics targeting the biology of aging and age-related chronic disease. The company works in drug discovery, aiming to produce treatments that address the underlying mechanisms of aging rather than managing individual disease symptoms after they appear.

Goodly lets employers offer student loan repayment as a workplace benefit, giving employees a structured way to pay down debt faster. It targets the B2B market, selling to companies that want to add a financial wellness perk to attract and retain talent. The product replaces ad-hoc, employee-managed repayment with an employer-administered contribution program.

Grabb-It delivers location-based dynamic digital out-of-home advertising, targeting brands and advertisers that want to reach audiences in the physical world. The platform replaces static, one-size-fits-all outdoor placements with ads that update based on location context. It also aggregates social and email channels, giving advertisers a unified surface for coordinated campaigns.

Grin builds a micromobility and payments platform serving riders across Latin America, with operations spanning Brazil, Mexico, Colombia, Chile, Uruguay, Argentina, and Peru. It connects consumers to short-distance transit options while handling the underlying payments infrastructure, replacing cash-based and fragmented local transport arrangements.

HappiLabs provides outsourced lab management to research scientists, startups, and biotech companies, pairing PhD-level former scientists with software tools to handle purchasing, inventory, supplier negotiations, safety compliance, and bookkeeping. The service replaces an in-house lab manager or purchasing department, freeing scientists from administrative work. Customers interact through tools like the ETA Dashboard and HappiApp to request purchases, track deliveries, and manage inventory.

Helicarrier (prev Buycoins) builds cryptocurrency infrastructure for African markets. Its Buycoins product gives users a platform to buy, sell, and manage crypto holdings, while Sendcash serves diaspora Africans who need to transfer money to recipients back home. The two products together replace a mix of traditional remittance services and fragmented crypto on-ramps across the continent.

Hepatx develops off-the-shelf, stem cell-based therapies for patients with end-stage liver disease, positioning the treatment as a direct alternative to liver transplant. The therapy targets the roughly 200,000 Americans each year who reach end-stage liver failure and face a severe shortage of donor organs. The work it replaces is organ transplant surgery, along with the prolonged waiting and high mortality that comes with relying on donor availability.

HeyDoctor delivers online primary care to patients who need routine services, such as birth control refills, UTI treatment, acne diagnosis, and cholesterol testing. Patients complete a visit through the app without insurance, video calls, or a waiting room. The platform replaces the traditional in-person doctor's visit for common, time-sensitive health needs.

Honeylove designs and sells bras, shapewear, and apparel for women who want support and structure without discomfort. Founded by performer Betsie Larkin, the company applies technical construction to categories where fit and function are typically compromised. Its products replace conventional shapewear and basics that prioritize aesthetics over wearability.

hypcloud operates as a tech-enabled commercial mortgage broker, connecting property owners and investors with financing for commercial real estate. It digitizes the brokerage process, replacing the manual, relationship-driven legwork that traditional commercial mortgage brokers handle across deal sourcing, lender matching, and transaction coordination.

iLabService builds a cloud-based lab operations management platform for scientific and industrial laboratories. It centralizes oversight of personnel, equipment, materials, procedures, and safety compliance into a single system, replacing fragmented manual tracking and disconnected tools. The platform targets lab operators who need unified visibility across daily operations and regulatory safety requirements.

Impactive (formerly Outvote) builds a distributed organizing platform for political campaigns, advocacy organizations, unions, and nonprofits. It centralizes outreach across peer-to-peer texting, phone banking, canvassing, broadcast messaging, and SMS fundraising into a single tool. The platform replaces a patchwork of separate tools that organizers previously used to recruit volunteers, contact voters and supporters, and track engagement at scale. The product is now offered under the ActBlue Field Tools brand.

INKHUNTER builds an augmented reality mobile app that lets people preview tattoo designs on their own skin before committing to permanent ink. Shoppers point their phone camera at their body to see how a chosen design looks in place, replacing the guesswork of imagining a tattoo from a flat reference image. The app also connects users to designs they can purchase, acting as a marketplace between buyers and tattoo artists or designers.

Inokyo builds cashierless checkout technology for physical retail stores, letting shoppers take items and leave without stopping at a register. The product replaces traditional point-of-sale lanes and cashier staffing, bringing the frictionless purchase flow of e-commerce into brick-and-mortar environments.

Inscribe builds AI-powered document fraud detection software for banks, credit unions, and lenders. It automates the manual review of financial documents submitted during underwriting, account opening, and bank account verification, catching forged and AI-generated fakes that human reviewers miss. Risk operations teams use it to cut fraud losses and reduce the analyst time spent on document queues.

Ixora builds digital outdoor environments for film productions, replacing the manual work of sourcing, designing, and rendering exterior settings. The product serves movie productions that need believable outdoor worlds created digitally rather than shot on location or constructed as physical sets.

JITX builds software-defined electronics tooling that converts engineering requirements, stackups, signal-integrity targets, and manufacturing rules into Python design code, then generates schematics, board structures, and manufacturable routing from that code. It targets hardware teams building high-frequency PCBs, replacing the manual work of HFSS simulation setup, layout markup, and rule handoffs that currently consumes days of senior SI engineer time. An AI proposes and edits the design code while JITX dispatches and closes the loop on HFSS simulations, keeping proprietary manufacturing rules local.

Khatabook builds a digital ledger app for small business owners in India, replacing the paper khata books merchants use to track credit and debit transactions with their customers. Business owners record what customers owe and what has been paid, eliminating manual bookkeeping. The platform also offers financial services such as lending to businesses that use it.

Kinside connects parents, child care providers, employers, and government agencies on a single platform that handles discovery, enrollment, and payments for child care. It replaces phone-tag searches and paper-based enrollment processes with real-time availability listings, one-click tour scheduling, and digital payments. Providers get a demand channel and enrollment management tool; employers use it to offer child care benefits to working parents.

Klarity builds enterprise AI for finance and G&A teams at large companies, covering two jobs: creating a digital twin of the business to surface operational gaps and inefficiencies, and processing contracts, invoices, and purchase orders into audit-ready data. It replaces manual document review and slow operational analysis that previously took quarters to complete.

Kobo360 builds a digital freight platform that connects manufacturers and cargo owners across Africa with truck operators to move goods from ports to factories and from factories to end customers. It uses data analytics and AI to optimize routes, coordinate pickups and deliveries, and give shippers real-time visibility into their cargo, replacing manual broker networks and opaque logistics coordination. The platform operates across seven African countries.

Kunduz builds an AI-powered homework help platform for secondary and university-prep students, combining an AI tutor with a network of human experts to deliver step-by-step answers to subject questions. Schools use it to bring student AI use into a structured, curriculum-aligned system, replacing unmonitored tools like ChatGPT with a platform that gives teachers visibility into where students are struggling. It replaces ad-hoc tutoring and uncontrolled AI use with a school-governed support layer.

LabelFlow builds release operations software for independent music labels, covering the full workflow from A&R demo intake through catalogue import, metadata management, and distribution tracking. Label managers use it to replace scattered tools like WhatsApp, spreadsheets, and manual store lookups with a single structured pipeline. Each release moves through a defined sequence of stops, keeping metadata, deliverables, and artist communications in one place.

Leena AI builds an agentic AI platform for enterprise back-office functions, serving HR, IT, Finance, and Procurement teams at large global enterprises. It ingests a company's internal knowledge and deploys pre-built, pre-trained AI agents that answer employee questions and resolve support tickets automatically, replacing the manual triage work that consumes HR, IT, and Finance staff. Employees interact through tools they already use, such as Slack and Microsoft Teams.

LemonBox Health sells personalized daily supplement packs to Chinese consumers, replacing the guesswork of self-selecting vitamins. Shoppers complete a diet-frequency questionnaire scored by the proprietary LemonAlgo system, built by a team of Chinese and U.S. registered dietitians, and receive a custom single-serving pack formulated from U.S.-manufactured ingredients and shipped directly to their door.

Lowkey builds a platform for gamers to capture, edit, and share highlight moments from their gameplay. It targets consumer gaming audiences who want to clip and distribute standout in-game moments without manual screen recording or video editing workflows. Niantic acquired the company in November 2021.

Mark Cuban Cost Plus Drug Company, PBC manufactures and sells affordable generic medications that would otherwise carry high prices in the traditional pharmaceutical supply chain. It serves patients and consumers who need generic drugs but face steep costs at conventional pharmacies. The company takes the place of the standard drug pricing model by sourcing and producing generics at a fraction of the typical retail price.

Medinas Health builds a cloud platform that helps hospitals track, manage, and trade medical equipment. Hospitals use it to handle asset inventory and to buy or sell surplus devices, replacing manual tracking processes and fragmented secondary-market transactions.

MentalHappy builds a HIPAA-compliant platform for mental health providers and health systems to run group therapy and support groups online. It handles scheduling, virtual sessions, member check-ins, secure chat, and resource sharing, replacing the manual administrative work that providers otherwise do across disconnected tools. AI-driven analytics flag at-risk group members and surface engagement data to help providers manage group outcomes.

Meru Health delivers online mental health treatment for adults dealing with depression, anxiety, and burnout. Patients work with licensed therapists and psychiatrists through a smartphone program that combines scheduled video sessions, async chat, guided behavioral and mindfulness exercises, and a biofeedback breathing device. The program replaces the patchwork of in-person therapy, standalone meditation apps, and crisis helplines with a single, clinician-supervised 12-week course.

Modern Treasury builds payment operations infrastructure for companies that move money at scale. Its API and web application cover the full cycle: customer onboarding and KYC, account creation, payment initiation across ACH, RTP, FedNow, wires, push-to-card, and stablecoins, through to reconciliation and reporting. It replaces bank portals, manual CSV uploads, and the patchwork of separate compliance vendors, ledgers, and payment tools that engineering and finance teams otherwise stitch together.

Momentus builds and operates in-space transport and service vehicles, moving satellites and payloads between orbits after launch vehicles drop them off. The vehicles run on water plasma propulsion, cutting the cost and energy of last-mile delivery in space. Customers include private satellite operators, government agencies, and research organizations that would otherwise be limited to the orbit their launch vehicle targets.

Mutiny builds an AI sales assistant for enterprise sales and marketing teams. It generates personalized decks, deal rooms, business cases, and mutual action plans from call recordings, emails, and CRM data, replacing the manual asset creation that reps otherwise do by hand. The platform also handles pre-call prep and post-call follow-up, so reps spend their time with buyers instead of on administrative work.

Mylk Guys built a national e-commerce store selling vegan food and lifestyle products, targeting consumers who wanted plant-based goods shipped directly to their door. It replaced specialty in-store shopping by aggregating vegan brands across food, beauty, healthcare, and home goods into a single online destination. The company used purchase data to identify and exclusively launch products it predicted would perform well. Mylk Guys has since shut down, citing thin food margins and high logistics costs.

Mytos builds automated cell manufacturing systems for regenerative medicine producers. Its iDEM technology replicates the standard 2D flask process used in manual cell culture inside closed, automated hardware, converting stem cells into specific therapeutic cell types, such as neurons, corneal cells, and bone cells, over multi-week production runs. This replaces the skilled manual laboratory work that today makes stem-cell therapies too costly and slow to reach patients at scale.

Names & Faces builds visual people directories for organizations, giving every employee a searchable, up-to-date reference for who works where and how they connect. The product replaces static org charts, outdated intranet pages, and tribal knowledge by pulling live data into a single, customizable index of people and teams. New joiners and senior leaders alike use it to find colleagues, understand reporting structures, and make contact quickly.

Nestor builds a skills-based talent management platform for HR teams and people leaders at mid-to-large enterprises. It maps employee skills against a library of over 20,000 capabilities, surfaces gaps, and uses AI matching to connect workers to internal roles, projects, and learning paths. It replaces manual skills audits, ad-hoc succession planning, and disconnected performance and learning tools.

Nova builds an investor management platform for private funds, centralizing digital subscriptions, data rooms, and investor communications in one place. It replaces fragmented, paper-heavy processes that fund managers use to onboard investors and share fund documents. The platform serves the back-office needs of private fund operators from subscription to ongoing LP relations.

numericcal, inc. builds distributed AI systems for industrial process monitoring and optimization in automotive and manufacturing operations. The platform ingests unstructured sensory data, including video and audio, to handle anomaly detection, asset detection and tracking, and workforce management. It replaces centralized cloud processing by splitting workloads across on-premises edge hardware and multiple cloud providers, cutting operating costs while handling greater data volumes.

OkCredit builds a digital bookkeeping app for Indian small merchants who extend informal credit to customers and suppliers. Merchants use it to log credit entries, set credit limits, and send automated payment reminders, replacing handwritten ledgers and manual follow-up. The product targets the tens of millions of Indian SMBs whose credit sales have historically lived on paper with no reliable way to track or recover what they are owed.

OneGraph builds a unified GraphQL layer that connects disparate third-party APIs, including Twitter, GitHub, Stripe, and Salesforce, into a single query interface. Developers use it in place of writing and maintaining separate integrations for each service. OneGraph was acquired by Netlify in Q4 2021.

OpenWrench builds facilities maintenance software for retail and restaurant chains. Store managers, operations teams, and vendors use one platform to report issues, track repairs, schedule inspections, and coordinate recurring maintenance tasks. It replaces scattered communication channels and manual tracking that multi-location operators use to manage vendors and keep their physical locations running.

Optic builds open-source tools that give engineering teams version control for API behavior. Developers use it to document API changes, run API-focused code reviews, and catch breaking changes before they ship to production. It replaces manual API diffing and ad-hoc review processes by bringing Git-style workflows to OpenAPI specs.

OWNY builds an all-in-one capital management platform for businesses that need to issue financial instruments, manage investors, and run treasury operations. It replaces the patchwork of banks, spreadsheets, and legal tools that founders and finance teams use to administer Funds, SAFEs, and Notes. The platform also handles multi-currency accounts, global ACH and wire payments, and optional crypto custody through Coinbase Institutional.

Oxygen built a digital banking platform for freelancers, gig workers, and small business owners, replacing traditional bank accounts with mobile-first personal and business accounts tailored to variable-income earners. The platform offered spending, deposits, and card services designed for entrepreneurs and mid-to-high income millennials who found conventional banking a poor fit. Services are currently inactive while the company works on new initiatives.

Paladin builds a drone-as-first-responder platform for public safety agencies. When a 911 call comes in, the system autonomously dispatches a drone from a fire station to the scene within 90 seconds, streaming live aerial video to responders before any unit arrives. This replaces the blind approach to an incident, giving dispatchers and first responders ground-truth situational awareness on fire size, exact location, and scene conditions before they pull up.

Papa connects older adults and families to vetted companions, called Papa Pals, who provide in-person help with social support, everyday tasks, and transportation. Health plans, Medicare Advantage and Medicaid programs, and employers offer Papa as a covered benefit to members and employees. The service replaces informal or absent support networks for people aging in place or facing social isolation.

Passenger AI builds software for robotaxi fleet operations, serving autonomous vehicle operators. The platform handles the operational layer that human dispatchers and coordinators would otherwise manage, enabling companies to run driverless ride services at scale.

Penta Medical builds smart hardware for injury recovery and prevention, serving athletic teams and sports medicine doctors. The platform tracks athlete health data, surfaces preventative statistics benchmarked across the field, and delivers customized treatment protocols, replacing manual injury tracking and ad hoc rehabilitation workflows.

Perception Biosystems builds automated, flexible manufacturing systems for gene therapy production, replacing large facilities, extensive labor, and complex regulatory processes with robotics and code. Its robotic lab compresses the time and cost required to produce gene therapies for human clinical trials, making it viable to pursue rare disease targets that conventional gene therapy factories cannot serve economically.

Phiar builds AI-powered augmented reality navigation software for drivers, running on smartphones and in-vehicle displays. Its road-understanding AI operates entirely on-device, in real time, without requiring cloud compute. The product replaces conventional map overlays with AR-based wayfinding that layers navigation cues directly onto the driver's view of the road.

Pine Park Health delivers primary care directly inside senior living communities, sending board-certified clinicians into residents' homes to handle routine checkups, chronic disease management, and urgent concerns. The model replaces the traditional outpatient visit, cutting out long drives, waiting rooms, and hospital trips that pose outsized health risks to older adults. Clinicians are embedded in each community on a regular schedule and coordinate directly with facility staff in assisted living and memory care settings.

Pocket Worlds builds and operates live social virtual worlds, targeting players who want persistent avatar-driven communities for fashion, socializing, and creative expression. Its portfolio includes Highrise, Everskies, and Hotel Hideaway, each built around a distinct community. Through its internal technology division Pocket Labs, it develops shared infrastructure covering content creation, real-time analytics, marketing, trust and safety, and live content production across all titles.

Prodigal builds AI agents and automation software for loan servicers and debt collectors in consumer finance. Its platform handles end-to-end collections operations across voice and digital channels, replacing manual agent work with automated outreach, real-time call notes, QA scoring, and payment orchestration. Customers in auto finance, lending, and healthcare revenue cycle use it to recover payments and run leaner servicing teams.

Purple Plate operates delivery-native virtual kitchens that extend the geographic reach of existing restaurant brands. It handles cooking, packaging, and fulfillment from its own staffed facilities, letting restaurant partners serve delivery and pickup customers in areas beyond their physical locations. The model replaces the need for a restaurant to open a new brick-and-mortar site to grow its delivery footprint.

Quickchat AI builds a platform that lets companies create and deploy multilingual AI agents powered by large language models like GPT and Claude. The agents handle customer support, sales, lead qualification, and internal helpdesk conversations across websites, WhatsApp, Instagram, Telegram, Shopify, Zendesk, and other channels. The product replaces manually staffed chat workflows by reading a company's own documentation, taking actions, and returning traceable, grounded answers.

Quo (fka OpenPhone) builds a shared business phone system for small businesses and startups, giving teams a single number, inbox, and conversation history for calls, texts, and voicemails. It replaces a patchwork of personal numbers and consumer messaging apps with a dedicated business line that multiple teammates can answer, monitor, and annotate together. Built-in call routing, an AI agent that picks up when staff cannot, and a lightweight CRM eliminate the need to track customer conversations across separate tools.

Radix Labs builds operating system software for biology laboratories, giving lab teams a unified platform to coordinate instruments, workflows, and data. It targets biotech and healthcare research environments, replacing the fragmented mix of manual tracking, spreadsheets, and siloed instrument software that researchers use to run experiments day to day.

Rain Neuromorphics builds neuromorphic AI chips that implement neural networks in physical hardware rather than software simulation. The core product, the Memristive Nanowire Neural Network (MN3), uses electroceramics, nanofabrication, and spiking-neuron architectures to deliver on-chip learning at a fraction of the power consumed by conventional GPUs and CPUs. The chip targets any device that runs neural network inference or training, replacing energy-intensive silicon processors with a physical analog of the brain.

Rebellyous Foods manufactures plant-based chicken products, including nuggets, patties, and tenders, for K-12 schools and foodservice operators. The company builds its own high-throughput production equipment and processes to bring the cost of plant-based meat down to the level of conventional animal-based chicken. That manufacturing focus replaces the standard approach of adapting off-the-shelf food production lines to plant-based ingredients.

Regology builds an AI-powered regulatory compliance platform for compliance, legal, risk, and operations teams at enterprises. The platform covers U.S. federal, all 50 state, and global jurisdictions through a continuously updated law and regulation library, replacing manual regulatory research and ad hoc change tracking. Three specialized AI agents handle jurisdiction-specific change alerts, mapping regulatory shifts to internal policies and controls, and generating plain-language summaries and cross-jurisdictional comparisons.

Rejuvenation Technologies Inc. develops mRNA-based therapies that lengthen telomeres, the protective DNA sequences that shorten as cells divide and age. Delivering TERT mRNA can reverse more than a decade of telomere shortening within days, targeting diseases driven by critically short telomeres, including pulmonary fibrosis, liver disease, and bone marrow failure. The company is translating this approach from the lab into clinical trials, replacing the absence of any approved treatment that addresses cellular aging at the chromosomal level.

RevenueCat builds a mobile SDK and API that handles in-app subscription infrastructure for iOS, Android, and the web. App developers use it to manage purchase flows, receipt validation, and subscription data across the App Store, Google Play, and other platforms, replacing the custom backend work each store's billing system would otherwise require. Engineering, product, marketing, support, and data teams each get purpose-built tooling on top of that single subscription data layer.

Satchel builds financial tools for businesses, replacing manual or fragmented money-management workflows with a unified platform. The company targets business owners who need clearer control over cash flow, payments, and financial operations in one place.

Scanwell Health builds smartphone-based diagnostic tools that let patients test for illnesses at home and receive results the same day. Its first product is an FDA-cleared, over-the-counter app paired with a physical test kit that diagnoses urinary tract infections and connects users to treatment, replacing a clinic visit for a condition that would otherwise require a doctor's appointment or urgent care trip.

Shelf Engine builds an AI-driven ordering platform for grocery retailers, predicting the right quantity of perishable goods to stock at the SKU and store level. It replaces manual or gut-driven buying decisions that routinely lead to spoilage or out-of-stocks. Retailers gain higher sales on perishables while cutting the food waste that erodes margins.

ShopWith builds a mobile live-shopping platform aimed at Gen Z consumers, combining real-time video with direct purchasing in the way broadcast shopping channels like QVC did for earlier generations. The product targets young buyers who discover and buy products through entertainment-style video rather than traditional e-commerce browsing.

SkydropX builds a logistics management platform for e-commerce and retail businesses in Mexico. It handles the end-to-end shipping workflow, from carrier selection and label generation to shipment tracking, delivery time estimation, and returns, work that merchants otherwise coordinate manually across multiple carriers. Its AI Dispatch tool centralizes these operations so that businesses control the full post-purchase experience without stitching together separate tools.

SPATE builds an AI-powered trend forecasting platform for beauty, wellness, and food and beverage brands. It analyzes consumer signals across Google Search, TikTok, Instagram, and Reddit to surface emerging ingredients, product categories, and whitespace opportunities before they peak. The platform replaces manual market research and analyst reports with a self-serve dashboard that guides product development and competitive strategy.

Spero Foods makes plant-based dairy products designed to match the taste and texture of conventional staples at an affordable price point. Using proprietary process engineering backed by patent applications across multiple markets, the company produces plant-based alternatives to foods consumers already eat daily. The products target health-conscious and environmentally minded consumers who would otherwise buy traditional animal dairy.

Synkrino Biotherapeutics builds an AI-driven drug discovery system, SATIS, designed to identify therapeutic candidates without the biases that shape traditional discovery workflows. The platform targets the early-stage research bottleneck in biotech, replacing manual, hypothesis-constrained screening with automated, data-driven candidate identification.

Tall Poppy builds digital safety tools and services that protect employees from online harassment. It serves companies that need to reduce personal security risk for their staff, handling both preventive measures to stop harassment before it escalates and hands-on incident response when attacks occur. The product replaces ad hoc, uncoordinated responses that employees and HR teams would otherwise navigate on their own.

TENDERD builds an AI and IoT platform that connects fleets, equipment, and worksites to give energy, logistics, construction, and mining companies a single view of their physical operations. The platform replaces manual tracking and siloed reporting with real-time GPS monitoring, predictive maintenance alerts, driver safety scoring, fuel analytics, and automated cost management. Operations teams use it to cut downtime, reduce fuel waste and emissions, and coordinate equipment allocation across field sites.

The Buttermilk Company sells direct-to-consumer meal kits built around authentic ethnic recipes sourced from local community cooks. Each kit contains fresh, preservative-free ingredients portioned for a single dish, letting home cooks produce a from-scratch meal in five minutes. The product replaces the time and skill required to source specialty ingredients and follow complex traditional recipes from scratch.

The Good Food Institute accelerates the development of plant-based meat, cultivated meat, and fermentation-derived proteins as replacements for conventional animal agriculture. A nonprofit operating internationally, it supports scientists, entrepreneurs, and food companies with open-access research, technical tools, and industry resources. Its work targets the environmental strain, disease risk, and resource inefficiency built into today's meat supply chain.

The Supplant Company makes a sugar blend derived from plant fiber, targeting food and beverage brands that want a drop-in sweetener with lower calories, a lower glycemic response, and prebiotic properties. The ingredient is extracted from agricultural byproducts, such as corn cobs and wheat straw, that are ordinarily discarded outside the food supply. It replaces conventional sugar in finished products without altering their taste, texture, or appearance.

Titan delivers wealth management to high-earning technology professionals, pairing each client with a licensed advisor backed by a team of specialists including Certified Financial Planners. The platform targets employees at leading tech companies navigating equity compensation, liquidity events, and career transitions. It replaces the traditional model that reserved dedicated advisory relationships for ultra-high-net-worth clients by combining AI-powered tooling with specialist human advice at a low annual fee.

UBITS builds a Spanish-language talent management platform for Latin American companies, covering the full employee lifecycle from recruitment and learning to performance reviews and engagement surveys. HR and L&D teams use it to hire, train, and develop staff in one place, replacing a mix of standalone tools and manual processes. An AI tutor guides learners, an AI recruiting agent screens and interviews candidates, and analytics surface decisions across the workforce.

User Hero builds a centralized repository for user research, serving product teams at B2B SaaS companies. It organizes studies, transcribes interviews, supports collaborative note-taking, and lets teams tag and search observations across sessions. The product replaces scattered documents, spreadsheets, and manual synthesis by automatically generating reports and rainbow charts from collected research.

Verse Medical builds software for in-home healthcare, connecting the fragmented network of vendors and nurses who coordinate care for patients recovering outside a hospital. The existing process runs on faxes and disconnected suppliers; Verse replaces that with a unified platform that keeps high-quality care flowing reliably to patients at home.

Vimcal builds a calendar application for founders, executives, and executive assistants who manage dense meeting schedules. It replaces sluggish calendar tools and manual availability-sharing workflows with keyboard-driven navigation, sub-100ms response times, and AI-assisted scheduling. Built-in time-zone coordination, unified multi-account views, and a dedicated executive assistant product handle the operational overhead that high-volume scheduling creates.

Warpdrive by Synthetic Minds converts screen recordings into desktop automations and on-screen workflow guides using program synthesis. A user records their screen, and the compiler analyzes the recording, synthesizes executable code from it, and produces either an unattended automation or a step-by-step guide within seconds. It targets business teams, replacing the manual work of scripting or documenting repetitive desktop workflows.

Xkit builds a universal CRM integration layer for B2B SaaS developers. Instead of engineering separate integrations for each CRM a customer uses, developers connect once to Xkit's standard API and get coverage across every CRM setup, including custom fields, objects, and workflows. The product replaces the recurring engineering work of building and maintaining bespoke CRM connectors for each end customer's configuration.

ZiffyHomes builds rental management software for Indian landlords and brokers, handling the full tenancy lifecycle: rent collection, tenant onboarding, agreement generation, and maintenance tracking. It replaces the manual, fragmented work of managing residential properties across India's urban rental market. Originally a managed co-living operator, the company has rebuilt as a pure software platform targeting brokers and property owners directly.